Trauma was the suspected etiology in this case. Because of the spasm of the iris muscle, as evidence by the miotic pupil, the clinical diagnosis was secondary acute anterior uveitis with hyphema. After a couple of hours, the hyphema appeared to clot in the anterior chamber and then bleed again during restraint. The menace response was present in the right eye but absent in the left eye. Lens position and pupillary light responses were normal, and the withdrawal response to bright light directed into the eye (that is, the dazzle reflex) was present in both eyes. The physical exam was normal otherwise.īiomicroscopic examination of the left eye with a portable slit lamp (SL-15, Kowa Optimed, Torrance, CA) revealed diffuse hemorrhage and a fibrin clot in the anterior chamber. Facial features were symmetrical, and there was no facial or periorbital swelling or tenderness. No obvious foreign body or corneal scratch was noted grossly, and there was no fluorescein dye uptake by the cornea. Marked hemorrhage in the ventral anterior chamber nearly obscured the miotic pupil, and the iris was a deeper yellow color than the pale yellow-green of the right eye. Research technicians played with the kittens every day for socialization and acclimation purposes, but did not detect problems with any of the kittens’ eyes.įour weeks into the acclimation period (prior to initiation of the research protocol), one 1.3-kg energetic intact male kitten was reported to have hyphema and blepharospasm in the left eye. Kittens were given a physical exam on arrival, and no abnormalities were noted. Food and water bowls and litter boxes were placed on the concrete floor, and airline crates were used to provide both hiding places and elevated resting surfaces. Covered pens were constructed of galvanized fencing measuring 58 × 127 × 76 in., with solid stainless steel panels on the bottom half of the side panels and a sliding latched gate for entrance. At the request of the principal investigator, animals were not vaccinated. Vendor health summaries indicated that cat colonies were seronegative for feline immunodeficiency virus, feline infectious peritonitis, feline leukemia virus, calicivirus, herpesvirus, coronavirus, panleukopenia virus, syncytical virus, Toxoplasma gondii, and Chlamydia psittaci. Twenty-eight 7-wk-old domestic shorthair kittens were obtained from a commercial feline vendor for an IACUC-approved study of feline immunodeficiency virus pathogenesis.
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